Heejin Lee; Kangmo Ahn; Youngshin Han; Sang-Jin Chung

doi:10.5720/kjcn.2013.18.5.515

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Original Article
Effects of Nutrition Education Promoting Vegetable, Fruit, and Fish Intake on the Severity of Atopic Dermatitis in Children: Results from a One-year Follow Up Study: Heejin Lee, Kangmo Ahn, Youngshin Han, Sang-Jin Chung; Korean Journal of Community Nutrition 2013;18(5):515-524.
DOI: https://doi.org/10.5720/kjcn.2013.18.5.515
Published online: October 31, 2013

Department of Foods and Nutrition, Kookmin University, Seoul, Korea.

¹Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Corresponding author: Sang-Jin Chung, 861-1 Jeongneungdong, Seongbukgu, Department of Foods and Nutrition, Kookmin University, Seoul 136-702, Korea. Tel: (02) 910-4777, Fax: (02) 910-5249, schung@kookmin.ac.kr

• Received: April 19, 2013 • Revised: August 13, 2013 • Accepted: October 15, 2013

This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Abstract
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REFERENCES

Abstract

Atopic dermatitis (AD) is believed to be associated with the intake of antioxidant nutrients and fatty acids due to its immunological dysfunction. The purpose of this study was to examine the effects of nutrition education promoting vegetable, fruit, and fish intake on the severity of AD in children. Children with AD aged 6 months to 5 years were randomly assigned into education and control groups, and followed for 1 year. Seventy-six children completed the study (38 for control, 38 for education). The education group received education promoting the intakes of antioxidant-rich foods (vegetables, fruits) and n-3 fatty acid foods (fish). A 24-hour food recall was collected for the diet information. After education, all vegetables (p < 0.001), fruits (p < 0.01), and fish (p < 0.05) intakes per 1000 kcal increased significantly in the education group, whereas only vegetable intake increased in the control group (p < 0.001). The SCORAD index, the severity of atopic dermatitis, decreased significantly in the education group (p < 0.05). Increased consumption of dietary vitamin E was significantly associated with reduction in the SCORAD index, after adjusting for age and gender (p < 0.05). A nutritional education program to increase vegetable, fruit, and fish intake may be effective in reducing the severity of AD, and vitamin E intake may be associated with the decreased severity of AD. More controlled studies on the relationship between these intakes and severity of AD, with intensive diet and/or supplement intervention programs, are needed to obtain conclusive results.
Keywords: atopic dermatitis; children; severity; fruit and vegetable; vitamin E

NOTES

This work was supported by the Korea Research Foundation Grant funded by the Korean Government (MOEHRD) (KRF-2007-331-C00281)

This work was supported by the research program 2012 of Kookmin University in Korea

REFERENCES

1. Alm B, Aberg N, Erdes L, Möllborg P, Pettersson R, Norvenius SG, Goksör E, Wennergren G. Early introduction of fish decreases the risk of eczema in infants. Arch Dis Child 2009; 94(1): 11-15.Article PubMed
2. Arslanoglu S, Moro GE, Schmitt J, Tandoi L, Rizzardi S, Boehm G. Early dietary intervention with a mixture of prebiotic oligosaccharides reduces the incidence of allergic manifestations and infections during the first two years of life. J Nutr 2008; 138(6): 1091-1095.Article PubMed
3. Boguniewicz M, Leung DY. Atopic dermatitis: a disease ofaltered skin barrier and immune dysregulation. Immunol Rev 2011; 242: 233-246.Article PubMed PMC
4. Chatzi L, Apostolaki G, Bibakis I, Skypala I, Bibaki-Liakou V, Tzanakis N, Kogevinas M, Cullinan P. Protective effect of fruits, vegetables and the Mediterranean diet on asthma and allergies among children in Crete. Thorax 2007; 62(8): 677-683.Article PubMed PMC
5. Devereux G, Seaton A. Diet as a risk factor for atopy and asthma. J Allergy Clin Immunol 2005; 115(6): 1109-1117.Article PubMed
6. Devereux G, Turner SW, Craig LC, McNeill G, Martindale S, Harbour PJ, Helms PJ, Seaton A. Low maternal vitamin E intake during pregnancy is associated with asthma in 5-year-old children. Am J Respir Crit Care Med 2006; 174(5): 499-507.Article PubMed
7. Eriksen BB, Kåre DL. Open trial of supplements of omega 3 and 6 fatty acids, vitamins and minerals in atopic dermatitis. J Dermatolog Treat 2006; 17(2): 82-85.Article PubMed
8. Fitzsimon N, Fallon U, O'Mahony D, Loftus BG, Bury G, Murphy AW, Kelleher CC. Mother's dietary patterns during pregnancy and risk of asthma symptoms in children at 3 years. Ir Med J 2007; 100(8): suppl 27-suppl 32.PubMed
9. Fogarty A, Lewis S, Weiss S, Britton J. Dietary vitamin E, IgE concentrations, and atopy. Lancet 2000; 356(9241): 1573-1574.Article PubMed
10. Kremmyda LS, Vlachava M, Noakes PS, Diaper ND, Miles EA, Calder PC. Atopy risk in infants and children in relation to early exposure to fish, oily fish, or long-chain omega-3 fattyacids: a systematic review. Clin Rev Allergy Immunol 2011; 41(1): 36-66.Article PubMed PDF
11. Kull I, Bergström A, Lilja G, Pershagen G, Wickman M. Fish consumption during the first year of life and development of allergic diseases during childhood. Allergy 2006; 61(8): 1009-1015.Article PubMed
12. Kunz B. Clinical validation and guidelines for the SCORAD Index: consensus report of the European task force on atopic dermatitis. Dermatology 1997; 195: 10-19.Article PDF
13. Hijazi N, Abalkhail B, Seaton A. Diet and childhood asthma in a society in transition: a study in urban and rural Saudi Arabia. Thorax 2000; 55(9): 775-779.Article PubMed PMC
14. Javanbakht MH, Keshavarz SA, Djalali M, Siassi F, Eshraghian MR, Firooz A, Seirafi H, Ehsani AH, Chamari M, Mirshafiey A. Randomized controlled trial using vitamins E and D supplementation in atopic dermatitis. J Dermatolog Treat 2011; 22(3): 144-150.Article PubMed
15. Korean Nutrition Society. Dietary reference intakes for Koreans.
16. Lee JH, Kim EH, Cho JB, Kim HY, Suh JM, Ahn KM, Cheong HK, Lee SI. Comparison of prevalence and risk factors of atopic dermatitis by physical examination and questionnaire survey in elementary school children. Pediatr Allergy Respir Dis 2011; 21(3): 186-196.Article
17. Lee JS, Jo S, Lee H, Kang A, Chung SJ. Associated factors of severity of atopic dermatitis in children. Korean J Community Nutr 2010; 15(6): 776-782.
18. Lee S, Ahn K, Paik HY, Chung SJ. Serum immunoglobulin E (IgE) levels and dietary intake of Korean infants and young children with atopic dermatitis. Nutr Res Pract 2012; 6(5): 429-435.Article PubMed PMC
19. Li-Weber M, Giaisi M, Treiber MK, Krammer PH. Vitamin E inhibits IL-4 gene expression in peripheral blood T cells. Eur J Immunol 2002; 32(9): 2401-2408.Article PubMed
20. Malmberg KJ, Lenkei R, Petersson M, Ohlum T, Ichihara F, Glimelius B, Frödin JE, Masucci G, Kiessling R. A short-term dietary supplementation of high doses of vitamin E increases T helper 1 cytokine production in patients with advanced colorectal cancer. Clin Cancer Res 2002; 8(6): 1772-1778.PubMed
21. Martindale S, McNeill G, Devereux G, Campbell D, Russell G, Seaton A. Antioxidant intake in pregnancy in relation to wheeze and eczema in the first two years of life. Am J Respir Crit Care Med 2005; 171(2): 121-128.Article PubMed
22. Mayser P, Mayer K, Mahloudjian M, Benzing S, Krämer HJ, Schill WB, Seeger W, Grimminger F. A double-blind, randomized, placebo-controlled trial of n-3 versus n-6 fatty acid-based lipid infusion in atopic dermatitis. JPEN J Parenter Enteral Nutr 2002; 26(3): 151-158.Article PubMed
23. Njå F, Nystad W, Lødrup Carlsen KC, Hetlevik O, Carlsen KH. Effects of early intake of fruit or vegetables in relation to later asthma and allergic sensitization in school-age children. Acta Paediatr 2005; 94(2): 147-154.Article PubMed
24. Oh JW, Kim KE, Pyun BY, Lee HR, Choung JT, Hong SJ, Park KS, Lee SY, Song SW, Kim CH, Ahn KM, Nam SY, Shon MH, Kim WK, Lee MH, Kwon BC, Choi SY, Lee SY, Lee HB, Lee SI, Lee JS. Nationwide study for epidemiological change of atopic dermatitis in school aged children between 1995 and 2000 and kindergarten aged children in 2003 in Korea. Pediatr Allergy Respir Dis 2003; 13(4): 227-237.
25. Oh SY, Chung J, Kim MK, Kwon SO, Cho BH. Antioxidant nutrient intakes and corresponding biomarkers associated with the risk of atopic dermatitis in young children. Eur J Clin Nutr 2010; 64(3): 245-252.Article PubMed PDF
26. Seaton A, Godden DJ, Brown K. Increase in asthma: a more toxic environment or a more susceptible population? Thorax 1994; 49(2): 171-174.Article PubMed PMC
27. Senkal M, Geier B, Hannemann M, Deska T, Linseisen J, Wolfram G, Adolph M. Supplementation of omega-3 fatty acids in parenteral nutrition beneficially alters phospholipid fatty acid pattern. JPEN J Parenter Enteral Nutr 2007; 31(1): 12-17.
28. Tamay Z, Akcay A, Ones U, Guler N, Kilic G, Zencir M. Prevalence and risk factors for allergic rhinitis in primary school children. Int J Pediatr Otorhinolaryngol 2007; 71(3): 463-471.Article PubMed
29. The Korean Nutrition Society. Dietary reference intakes for Koreans, first revision. Seoul: The Korean Nutrition Society; 2010.
30. Tsoureli-Nikita E, Hercogova J, Lotti T, Menchini G. Evaluation of dietary intake of vitamin E in the treatment of atopic dermatitis: a study of the clinical course and evaluation ofthe immunoglobulin E serum levels. Int J Dermatol 2002; 41(3): 146-150.Article PubMed
31. Wong GW, Ko FW, Hui DS, Fok TF, Carr D, von Mutius E, Zhong NS, Chen YZ, Lai CK. Factors associated with difference in prevalence of asthma in children from three cities in China: multicentre epidemiological survey. BMJ 2004; 329(7464): 486.Article PubMed PMC

Table 1

General characteristics of the subjects

1) N (%)

2) Mean ± SD

SCORAD: Scoring index of atopic dermatitis

Table 2

Comparison of nutrient intakes of subjects before and after nutrition education (per 1000 kcal)

1) Mean ± SD

^*: p < 0.05, ^**: p < 0.01, ^***: p < 0.001: significantly different between pre-test and post-test by paired t-test in each group

Table 3

Comparison of vegetable,fruit and fish intakes of subjects before and after nutrition education (g/1000 kcal)

1) Mean ± SD

^*: p < 0.05, ^**: p < 0.01, ^***: p < 0.001: significantly different between pre-test and post-test by paired t-test

^#: p < 0.05: significantly different between control group and education group by student's t-test

Table 4

Comparison of SCORAD index of subjects before and after nutrition education

1) Mean ± SD

^*: p < 0.05, ^**: p < 0.01, ^***: p < 0.001: significantly different between pre-test and post-test by paired t-test

^#: p < 0.05: significantly different between control group and education group by ANCOVA after adjusting for age and sex

SCORAD: Scoring index of atopic dermatitis

Table 5

Severity change of Atopic Dermatitis by change of nutrient intakes per 1000 kcal

1) β coefficients and 95% CI were calculated by using simple and multiple linear regression analysis

SCORAD: Scoring index of atopic dermatitis

Figure & Data

REFERENCES

Citations

Citations to this article as recorded by

Nutritional Intervention for a Korean Adolescent with Atopic Dermatitis: a Case Report
Sunghee Kim, Sung-Im Lee, Shin-Sook Kang
Clinical Nutrition Research.2021; 10(4): 364. CrossRef
Evaluation of nutritional status and adequacy of energy and nutrient intakes among atopic dermatitis children under 12 years of age: based on Korea National Health and Nutrition Examination Survey data (2013–2015)
Hye Won Kim, Ji-Myung Kim
Journal of Nutrition and Health.2020; 53(2): 141. CrossRef

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Effects of Nutrition Education Promoting Vegetable, Fruit, and Fish Intake on the Severity of Atopic Dermatitis in Children: Results from a One-year Follow Up Study

Korean J Community Nutr. 2013;18(5):515-524. Published online October 31, 2013

DOI: https://doi.org/10.5720/kjcn.2013.18.5.515

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Effects of Nutrition Education Promoting Vegetable, Fruit, and Fish Intake on the Severity of Atopic Dermatitis in Children: Results from a One-year Follow Up Study

Table 1

General characteristics of the subjects

1) N (%)

2) Mean ± SD

SCORAD: Scoring index of atopic dermatitis

Table 2

Comparison of nutrient intakes of subjects before and after nutrition education (per 1000 kcal)

1) Mean ± SD

^*: p < 0.05, ^**: p < 0.01, ^***: p < 0.001: significantly different between pre-test and post-test by paired t-test in each group

Table 3

Comparison of vegetable,fruit and fish intakes of subjects before and after nutrition education (g/1000 kcal)

1) Mean ± SD

^*: p < 0.05, ^**: p < 0.01, ^***: p < 0.001: significantly different between pre-test and post-test by paired t-test

^#: p < 0.05: significantly different between control group and education group by student's t-test

Table 4

Comparison of SCORAD index of subjects before and after nutrition education

1) Mean ± SD

^*: p < 0.05, ^**: p < 0.01, ^***: p < 0.001: significantly different between pre-test and post-test by paired t-test

^#: p < 0.05: significantly different between control group and education group by ANCOVA after adjusting for age and sex

SCORAD: Scoring index of atopic dermatitis

Table 5

Severity change of Atopic Dermatitis by change of nutrient intakes per 1000 kcal

1) β coefficients and 95% CI were calculated by using simple and multiple linear regression analysis

SCORAD: Scoring index of atopic dermatitis

Table 1 General characteristics of the subjects

1) N (%)

2) Mean ± SD

SCORAD: Scoring index of atopic dermatitis

Table 2 Comparison of nutrient intakes of subjects before and after nutrition education (per 1000 kcal)

1) Mean ± SD

^*: p < 0.05, ^**: p < 0.01, ^***: p < 0.001: significantly different between pre-test and post-test by paired t-test in each group

Table 3 Comparison of vegetable,fruit and fish intakes of subjects before and after nutrition education (g/1000 kcal)

1) Mean ± SD

^*: p < 0.05, ^**: p < 0.01, ^***: p < 0.001: significantly different between pre-test and post-test by paired t-test

^#: p < 0.05: significantly different between control group and education group by student's t-test

Table 4 Comparison of SCORAD index of subjects before and after nutrition education

1) Mean ± SD

^*: p < 0.05, ^**: p < 0.01, ^***: p < 0.001: significantly different between pre-test and post-test by paired t-test

^#: p < 0.05: significantly different between control group and education group by ANCOVA after adjusting for age and sex

SCORAD: Scoring index of atopic dermatitis

Table 5 Severity change of Atopic Dermatitis by change of nutrient intakes per 1000 kcal

1) β coefficients and 95% CI were calculated by using simple and multiple linear regression analysis