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Thermic Effect of Food, Macronutrient Oxidation Rate and Satiety of Medium-chain Triglyceride
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Hee Ryoung Son, Myung Ju Lee, Eun Kyung Kim
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Korean J Community Nutr 2015;20(6):468-478. Published online December 31, 2015
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DOI: https://doi.org/10.5720/kjcn.2015.20.6.468
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Abstract
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- OBJECTIVES
The objective of this study was to evaluate the thermic effects, the macronutrient oxidation rates and the satiety of medium-chain triglycerides (MCT).
METHODS
The thermic effects of two meals containing MCT or long-chain triglycerides (LCT) were compared in ten healthy men (mean age 24.4 +/- 2.9 years). Energy content of the meal was 30% of resting metabolic rate of each subject. Metabolic rate and macronutrient oxidation rate were measured before the meals and for 6 hours after the meals by indirect calorimetry. Satiety was estimated by using visual analogue scales (VAS) at 8 times (before the meal and for 6 hours after meal).
RESULTS
Total thermic effect of MCT meal (42.8 kcal, 8.0% of energy intake) was significantly higher than that (26.8 kcal, 5.1% of energy intake) of the LCT meal. Mean postprandial oxygen consumption was also significantly different between the two types of meals (MCT meal: 0.29 +/- 0.35 L/min, LCT meal: 0.28 +/- 0.27 L/min). There were no significant differences in total postprandial carbohydrate and fat oxidation rates between the two meals. However, from 30 to 120 minutes after consumption of meals, the fat oxidation rate of MCT meal was significantly higher than that of the LCT meal. Comparison of satiety values (hunger, fullness and appetite) between the two meals showed that MCT meal maintained satiety for a longer time than the LCT meal.
CONCLUSIONS
This study showed the possibility that long-term substitution of MCT for LCT would produce weight loss if energy intake remained constant.
- [English]
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Relationship between Ferric Reducing Antioxidant Power and Metabolic Risk Factors in Korean Women Living in Seoul
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Ho Kyung Kwak, Mee Sook Lee, So Young Lim, Sun Yoon
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Korean J Community Nutr 2008;13(1):91-99. Published online February 29, 2008
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Abstract
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- The present study was conducted to examine metabolic risk factors and total antioxidant capacity (TAC) of Korean females living in Seoul and to investigate the relationship between the metabolic risk factors and serum TAC. A total of 353 females aged between 20 and 64 participated in the study. Obesity indicators, blood pressure, serum lipid profile and fasting blood glucose were measured as metabolic risk factors. Ferric reducing antioxidant power (FRAP) assay was employed to determine serum TAC of subjects. Obesity indicators such as body mass index, waist circumference and waist-hip ratio were significantly higher in the participants aged > or = 50 y (older group) than in the participants aged 20-49 y (younger group) (p < 0.001). Blood pressure, serum total cholesterol (TC), riglyceride (TG) and fasting blood glucose were also significantly higher in the older group than in the younger group (p < 0.001), demonstrating significant positive correlations between age and MS risk factors. The association between FRAP and MS risk factors were also investigated. FRAP values showed significant positive correlations with age (p = 0.001), serum TG (p = 0.002) and TC (p = 0.03). A tendency of positive association between FRAP and waist circumference was observed without any significant difference (p = 0.06). Increased serum FRAP with central obesity and serum lipids may be interpreted as results of activation of antioxidant defense system against oxidative stress induced by metabolic syndrome (MS) constituent factors. However, to verify the function of FRAP as a potential biomarker of susceptibility to MS various contributors to the plasma antioxidant capacity and their biological relevance related to MS should be elucidated further.
- [English]
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Plasma LDL Particle Sizes Affect the Blood Lipid Profile and Dietary Intakes among Korean Adults
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Youn Kyoung Suh, Hyung Sook Kim, Jeong Sook Kim, Cheol Ho Kim, Haymie Choi
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Korean J Community Nutr 2004;9(1):58-65. Published online February 29, 2004
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Abstract
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- The purpose of this research was to examine the relationship between the plasma LDL particle size and blood lipid profile, dietary factors and anthropometric values (body mass index, waist circumference and waist/hip ratio). The subjects were 173 adults aged 23 to 81 years, selected from the Outpatient Clinic and Cardiovascular Department of the Seoul Municipal Hospital. Dietary data were obtained using a 3-day food record and analyzed using Korean and US nutrient databases. The subjects were divided into three groups by LDL particle size:type A (large buoyant LDL, > 25.5 nm, n = 96), type I (Intermediate LDL, 25.2 < or = - < or = 25.5 nm, n = 18), and type B (small dense LDL, < 25.2 nm, n = 59) groups. The type B group had higher age, waist circumference, and waist/hip ratio (WHR) than the type A and type I groups. Serum concentration of triglyceride, Apo B, LDL/HDL cholesterol ratio and atherogenic index were significantly higher in the type B group as compared to those in the other two groups. HDL cholesterol level and Apo A-I/Apo B ratio were significantly lower in the type B group than the other two groups. The plasma LDL particle size was highly correlated with triglyceride (r = -0.450), Apo B (r = -0.402) and HDL cholesterol (r = 0.418). However, there was no correlation between plasma LDL particle size and dietary intakes. This study showed that small dense LDL was an important biochemical risk factor that was associated with other risk factors.
- [English]
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A Comparative Study on the Serum Lipid Levels and the Dietary Intake of Physical Education Major and Non-Major Male Students
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Kyoung A Choi, Myung Hee Kim
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Korean J Community Nutr 2003;8(5):667-674. Published online October 31, 2003
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Abstract
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- The paper examines the effect of physical exercise on blood lipid with young male students. Our analysis is based on the body measurement, food intake and blood lipid component for 70 male students of Kongju National University who either major in physical exercise (group A) or do not major in physical exercise (group B). The average weight of group A is 71.97 +/- 10.79 kg while that of group B is 67.57 +/- 8.66 kg. The former is significantly higher (p < 0.05) than the latter. The SBP of group A (128.20 +/- 11.40 mmHg) is significantly (p < 0.001) higher than that of group B (136.27 +/- 13.18 mmHg). In terms of the intake of total kcal, group A marks significantly higher than group B; group A goes with 2190.26 +/- 581.96 kcal and group B goes with 2392.94 +/- 769.03 kcal. The comparative analysis of the three nutrient intake shows that the intake proportions for group A are carbohydrate 55.08 +/- 6.03%, protein 15.58 +/- 2.75%, and lipid 29.34 +/- 5.16% while the intake proportions for group B are carbohydrate 57.29 +/- 8.09%, protein 15.62 +/- 3.26%, and lipid 27.10 +/- 6.90%. For group A, the vitamin B1 intake amounts to 1.50 +/- 0.5 mg which fulfills 100% of RDA, and the niacin intake amounts to 16.57 +/- 5.54 mgN.E which is less than RDA. In contrast, both intakes for group B are more than the RDA. In the case with minerals except calcium, both group A and B mark more intake than RDA. Group A's calcium intake is 517.12 +/- 200.63 mg and group B's is 409.56 mg. The total cholesterol intake for group A is 447.00 +/- 245.08 mg which is significantly (p < 0.05) higher than for group B with 352.35 +/- 200.25 mg. The total cholesterol in the lipid of serum is 151.30 +/- 12.92 mg/dl for group A and 182.30 mg/dl for group B, where the dominance of group B over group A is true at the level of significance 0.01. In the case with triglyceride, group A is 107.57 +/- 31.60 mg/dl and group B is 108.07 +/- 33.93 mg/dl so that the group difference is non-significant. The HDLcholesterol for group A is 54.67 +/- 6.49 mg/dl which is significantly higher (p < 0.001) than for group B with 36.13 +/- 4.64 mg/dl. We conclude that regular exercise may have an effect on blood lipid metabolism among young males.
- [English]
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The Relationship between Serum Cholesterol Levels and Dietary Fatty Acid Patterns, Plasma Fatty Acids, and Other Lipid Profile among Korean Adults
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Jeong Sook Kim, Youn Kyoung Suh, Hyung Sook Kim, Kyung Ja Chang, Haymie Choi
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Korean J Community Nutr 2003;8(2):192-201. Published online April 30, 2003
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Abstract
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- The purposes of this research were to assess dietary fatty acid patterns and to elucidate the relationship between the serum cholesterol levels and dietary fatty acid patterns, plasma fatty acid compositions, BMI (body mass index), and other lipid profile. The subjects were 151 adults aged 23 to 80 years, selected from the Outpatient Clinic and Cardiovascular Department of the Seoul Municipal Hospital. Dietary data were obtained using three day food records. Sixteen dietary fatty acids were analyzed using Korean and US nutrient databases. The subjects were divided into three serum cholesterol levels: desirable (< 200 mg/dl, N = 44), borderline-risk (> or = 200 - < 240 mg/dl, N = 35), and high-risk (> or = 240 mg/dl, N = 72) groups. The high-risk group had higher BMI, waist, and waist to hip ratio (WHR) than the desirable and borderline-risk groups. Serum concentrations of triglyceride, LDL cholesterol and LDL/HDL cholesterol ratio were significantly higher in the high-risk group as compared to those in the other two groups. The serum cholesterol levels were highly correlated with BMI (r = 0.435), triglyceride (r = 0.425) and LDL/HDL cholesterol (r = 0.870) ratio. The highest fatty acid intake was from oleic acid (33 - 34% of total fatty acid intakes), which was followed by linoleic acid (27%), palmitic acid (19%), and stearic acid (7%). There was no correlation between the serum cholesterol levels and the dietary fatty acid intakes, polyunsaturated/monounsaturated/saturated fatty acids (P/M/S) and omega6/omega3 ratios. The correlation between plasma fatty acids such as myristic acid, oleic acid, linoleic acid, and docosahexaenoic acid and serum cholesterol levels was also weak.
- [English]
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Serum Lipids by Gender, Age and Lifestyle in Korean Adults
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Mi Kyung Kim
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Korean J Community Nutr 2000;5(1):109-119. Published online March 31, 2000
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Abstract
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- The purpose of this study was to measure serum lipids concentrations by gender and age, and to investigated the relation of serum lipids levels to cigarette smoking alcohol intake exercise and menopausal status in Korean adults. The subjects consisted of 463 healthy adult(29- men and 173 women) volunteers who were visiting the health Promotion Center in the Asan Medical Center from July 1, 1994 to July 22, 1994 Subjects were ambulatory free-living people and aged 20- 80 years, Anthropometric measurement was performed and serum triglyceride(TG), HDL-cholesterol and total cholesterol(TChol) concentrations were measure by automatic system(Hitachi 736-40). Data on life styles were obtained using structured questionnaires issued by a trained interviewer, All data were statistically analyzed by PC-SAS(Version 6.04) Serum concentrations of triglyceride and total cholesterol was higher(p<0.05) in men than in women, and serum HDL-cholesterol was lower(p<0.05) in men than in women. The prevalence of hyperlipidemia(TG>170 mg/dL and TChol>220 mg /dL) was 12.5% in men and 4.1% in women. The levels of serum triglyceride, total cholesterol and BMI increased with age in women. The distribution curves of serum triglyceride, total cholesterol and LDL-cholesterol of women were located in lower increased more rapidly with aging than in men, The distribution curves of BMI of women increased with aging after the thirties, The BMI of women was located in higher levels than of men in their sixties. The serum concentration of triglyceride and total cholesterol of male current-smokers and non-smokers were significantly(p<0.05) higher than those of ex-smokers. The concentrations triglyceride the male current0drinkers were higher(p<0.05) than those of male non-drinkers. In non-smokers and non-drinkers, serum TG concentration were lower (p<0.05) than those of current-smokers and current-drinkers. In exercisers, the serum triglyceride concentration was significantly(p<0.05) lower than in non-exercisers. In postmenopausal woman BMI and serum concentrations of TChol, TG and LDL-Chol were significantly by age and gender and smoking alcohol drinking, exercise and menopausal staus might be a better indicator to predict serum lipids in both genders.
- [English]
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Characteristics of the Anthropometry and Plasma Lipid Profiles of Patients with Simple and Combined Hypercholesterolemia
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Young Rahn Huh, Kum Hee Hwang, Hyeon Sook Lim
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Korean J Community Nutr 1999;4(2):186-193. Published online June 30, 1999
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Abstract
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- Recent epidemiologic and clinical students have shown that plasma cholesterol and triglyceride levels are independent risk factors for coronary heart disease. However, there is not much data on the characteristics of anthropometry and lipid profiles of hypercholesterolemic patients with hypertiglyceridemia. In this study, 112 hypercholesterolemic subjects(T-C 240mg/dl) were divided into two groups by their plasma triglyceride levels. We compared the anthropometric measurements and lipid profiles of the subjects between the two groups : the simples hypercholesterolemic group(SHC, TG<200mg/dl) and the combined hypercholesterolemic group(CHC, TG 250mg/dl). The distribution of the subjects into the SHC and CHC groups was 36.6% and 47.3%, respectively. The frequency of the CHC patients decreased with age. The subjects in this group had higher weight, BMI, HWR, cricumferences of mid arm, waist, hip and thigh, and skinfold thicknesses of biceps and triceps than those of the SHC subjects. The difference of plasma total cholesterol level was mainly due to the difference of VLDL-C levels. These differences resulted in the CHC subjects having higher atherogenic indexes and T-C/HDL-C ratios than those of the SHC subjects. Also, the former had higher Apo-B and insulin levels than those the latter. However, blood pressure, fasting blood glucose and HDL-C levels were not significantly different between the two groups. These results suggest that hypercholesterolemic patients with hypertriglyceridemia have riskier lipid profiles for CHD than those of patients with normal triglyceridemia. They also indicate that CHC is closely associated with glucose resistance syndrome(obesity, hyperglycemia, hyperinsulinemia and hypertriglyceridemia), and more prevalent in young people.
- [English]
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A Study on Factors Related to Recovery from Cerebrovascular Accidents
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bong soon choi, Myeung Hee Park, young Mee Jeoung
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Korean J Community Nutr 1997;2(4):539-546. Published online October 31, 1997
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Abstract
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- This study was designed to investigate factors related to recovery from cerebrovascular accidents(CVA). Medical charts of 100 CVA patients(40 males and 60 females) who had been treated at Bul-Guang hospital in Teagu from June to December 1994 were reviewed to assess their recovery from CVA. Not only types of CVA, blood pressure and serum cholesterol and triglyceride were factors affecting recovery from CVA, but also smoking and drinking status and food preference seemed to be important factors. The percentages of recovered patients were higher in the order of cerebral thrombosis(83.3%), subarachnoid hemorrhage(57.1%), cerebral embolism(50.0%), and cerebral hemorrhage(26.7%). Recovery rates of patients with serum cholesterol below 200mg/dl, 200-239mg/dl, over 240mg/dl were 81.8%, 66.6%, and 16.6% respectively. Recovery rates of patients with serum triglyceride below 160mg/dl, 160-209mg/dl, and oover 210mg/dl were 84.6%, 72.8%, and 35.7% respectively. Patients with standard weight recovered better than those with overweight or obesity. Recovery rates of underweight, standard weight, overweight and obesity patients were 73.3%, 85.7%, 45.8%, and 31.6% respectively. Smoking and drinking seemed to be important factors which inhibited recovery from CVA. Patients preferring spiced foods were recovered better than those preferring salty or pungent foods.
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