Korean Journal of Community Nutrition

Review

[English]
Mercury exposure is associated with obesity: a systematic review and meta-analysis: Jimin Jeon, Kyong Park; Korean J Community Nutr 2023;28(3):192-205. Published online June 30, 2023; DOI: https://doi.org/10.5720/kjcn.2023.28.3.192

Objectives
Previous studies have evaluated the association between mercury exposure and obesity but have yielded mixed conclusions. The aim of this study was to systematically review and summarize scientific evidence regarding the association between mercury exposure and obesity in the human population.
Methods
We conducted a systematic search of PubMed, Web of Science, Scopus, and Science Direct for articles related to mercury exposure and obesity. Meta-analyses of the highest and lowest categories of mercury levels were evaluated using a random effects model. Begg’s test was used to detect publication bias.
Results
A total of 9 articles were included. The pooled random effects odds ratio (OR) for mercury exposure and obesity of all 9 studies was 1.66 (95% confidence interval [CI]: 1.16-2.38). This positive association was evident in adults (OR: 1.61, 95% CI: 1.02-2.54) and among studies with Asian populations (OR: 2.00, 95% CI: 1.53-2.59), but not among those with North America/African populations (OR: 0.90, 95% CI: 0.50-1.65).
Conclusions
The present meta-analysis identified a positive association between mercury exposure and obesity. These findings suggest that toxic environmental metals such as mercury may be an important risk factor for obesity along with dietary habits and lifestyles.

Citations

Citations to this article as recorded by

Re-thinking the link between exposure to mercury and blood pressure
Xue Feng Hu, Allison Loan, Hing Man Chan
Archives of Toxicology.2025; 99(2): 481. CrossRef
Association between heavy metal exposure and biomarkers for non-alcoholic fatty liver disease in Korean adolescents
Dong-Wook Lee, Jongmin Oh, Yu Min Lee, Hyun-Joo Bae, Youn-Hee Lim
Heliyon.2024; 10(19): e37840. CrossRef

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Original Article

[English]
Effectiveness of Nutrition Intervention : Systematic Review & Meta-Analysis: Hae Young Lee, Hyun Ah Kim, Il Sun Yang, Chung Mo Nam, Eun Cheol Park; Korean J Community Nutr 2004;9(1):81-89. Published online February 29, 2004

Abstract PDF: A systematic review and meta-analysis of the literatures was conducted to evaluate the effectiveness of nutrition intervention by dietitian. The 31 studies that were all randomized controlled trials, were identified from computerized search of published researches on MEDLINE, Embase database until January, 2003 and review of reference lists. The main search terms were the combination "dietitian", "dietary intervention", "nutrition intervention" or "nutritional intervention" and "effectiveness". The subgroup analysis was performed by the publication year, quality score, type of disease, content of intervention, intervention provider, type of intervention (nutritional counseling and education/nutrition counseling and education + diet modification), method of intervention (individual/group/individual + group) and follow-up period. Two reviewers independently selected trials for inclusion, assessed the quality and extracted the data. The meta-analysis of 31 studies based on the random effect model showed that the medical nutrition therapy was significantly effective in treating the diseases (effect size 0.1715 ; 95% confidence interval 0.0938 - 0.2491). This study showed the clear evidence of the effectiveness of nutrition intervention through the meta-analysis. So the nutrition intervention by dietitian should be recommended and recognized as the effective therapy of treating the diseases. Also the nutrition intervention should be conducted regularly to maintain the effectiveness of the nutrition intervention. The nutrition intervention was significantly effective in treating the diseases on the random effect model (effect size :0.1715 ; 95% confidence interval 0.0938 - 0.2491).

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